multicentric reticulohistiocytosis: a case report

Multicentric reticulohistiocytosis with extra-mammillary Paget’s disease: a case report

Multicentric reticulohistiocytosis (MRH) is a very rare systemic disease with variable phenotypic presentation and a high rate of misdiagnosis. Here we describe a patient with MRH and extra-mammillary Paget's disease (EMPD), a diagnosis that has not previously been described in the literature.

Multicentric Reticulohistiocytosis Associated with Liver Carcinoma: Report of a Case

We report a unique case of multicentric reticulohistiocytosis (MRH) associated with liver carcinoma. A 61-year-old man presented with a 4-month history of nonpruritic, generalized, ruby-red papules and nodules, accompanied by fever, joint swelling and difficulty in swallowing. Skin histology showed polymorphic histiocyte infiltration with typical 'ground glass' cytoplasm. Further immunohistoche...

Multicentric reticulohistiocytosis with S100 protein positive staining: a case report.

Multicentric reticulohistiocytosis is a very rare systemic disease that affects skin, mucosa and joints. We reported a case of a woman with multicentric reticulohistiocytosis who presented typical skin syndromes and arthralgia. Immunohistochemical analysis showed positive staining for S100 protein, which was reported negative in the majority of previously presented cases. Other immunohistochemi...

Progressive multicentric reticulohistiocytosis.

S-100 Positive Multicentric Reticulohistiocytosis – Report of a Rare Case with Brief Review of Literature

Background: Multicentric reticulohistiocytosis (MRH) is a rare histiocytic proliferative disorder involving skin, mucosa and joints. Diagnosis is confirmed by histopathological examination. Case Report: A 45 year old patient presented with non-pruritic papules over the body and multiple joint pains. Histopathologically, the lesion was composed of oncocytic macrophages and multinucleate giant ce...

Cardiac engagement in multicentric reticulohistiocytosis: report of a case with fatal outcome and literature review.

Multicentric reticulohistiocytosis is a rare systemic disorder of unknown etiology characterized by severe destructive arthritis, development of cutaneous nodules and is in many cases associated with malignancy. In multicentric reticulohistiocytosis polyarticular, symmetric, erosive arthritis is common and progresses to mutilans arthritis in 45% of cases. Skin lesions are characterized by typic...